Welcome!
We are a theoretical research group working in computational immunology. We develop computational tools for the analysis of omics and flow data. We also collaborate with experimentalists and clinicians on translational infectious disease & fundamental immunology research projects.
Our research includes analyzing, modeling, and interpreting high-dimensional biomedical datasets, comprising single-cell or bulk omics assays, spatial assays, flow cytometry data and more. Approaches employed by and developed in our lab include - but are not limited to - mathematical models, computer simulations, and machine learning methods.
In computational method development, our primary objective is to create tools that facilitate the informative fusion of data from various sources, such as different modalities, technologies or diseases. We conceive, prototype and develop algorithms to this end, but also emphasize thorough benchmarking, usability, reproducibility and maintenance.
News
July 2nd 2025 We are currently recruiting a computational postdoc to join the infrastructure project of a newly funded large research consortium (SFB-TRR) on Circadian Medicine! See the joint job posting for all consortium projects and apply by August 8th. We are looking for independent, detail-oriented individuals that want to make a difference for the entire consortium by constructing high-quality data assets and innovative computational omics methods with a circadian twist. We offer the opportunity to work part-time (0.75FTE or more). Please reach out to lisa.buchauer@charite.de with questions. Prior experience with the Berlin computational ecosystem is considered a plus.
June 28th 2025
Lab members Mark, Jonathan and Lisa, together with departmental friends Lara and Josua, participated in Charité’s Long Night of Science and explained the immune system to an estimated 70 kids and their parents. Quite exhausting, but also very rewarding! Meanwhile, Roberta participated in the Science Slam where she talked about circadian single cell research.
May 20th 2025
We went on a group excursion hiking along Wannsee and crossing to the Peacock Island where we had a delicious picnic :-)
May 13th 2025
… and Roberta won the ISCO 2025 jury’s poster prize!
May 12th 2025
We attended the Innovations in Single-Cell Omics conference in Berlin where Jonathan, Roberta and Mark & Constantin presented their work on posters…
March 2nd 2025 Welcome Roberta, who is joining us for her MD thesis research!
February 1st 2025 Welcome Ishminder, who is joining us for his master’s thesis in Molecular Medicine!
For older items, see the Lab Chronicle.